首都醫(yī)科大學研究生導師介紹:徐群淵 正文
姓名:徐群淵性別:男職稱:教授招生院所:基礎(chǔ)醫(yī)學院招生類型:科學學位(博)科學學位(碩)招生專業(yè):神經(jīng)生物學(博)神經(jīng)生物學(碩)研究方向名稱:神經(jīng)生物學電子信箱:xuqy@ccmu.edu.cn
社會任職
1.中國優(yōu)生科學學會副會長
2.北京醫(yī)師協(xié)會監(jiān)事
3.北京神經(jīng)科學會副理事長
4.北京專家聯(lián)誼會顧問
5.中國解剖學會名譽理事長
6.解剖學報副主編
7.FoundingEditorof"NeuralRegenerationResearch"
8.轉(zhuǎn)化醫(yī)學研究常務副主編
個人簡歷
1.195809-196307:北京醫(yī)學院(現(xiàn)北京大學醫(yī)學部)醫(yī)療系本科生
2.196309-199012:北京第二醫(yī)學院(現(xiàn)首都醫(yī)科大學)解剖教研室助教-教授
3.198105-198807:瑞典KarolinskaInstitute解剖系(現(xiàn)神經(jīng)科學系)研修(獲博士學位)
4.198511-200204:首都醫(yī)科大學校長
5.198810-201210:北京神經(jīng)科學研究所所長
6.199012-0:首都醫(yī)科大學教授
7.200201-0:北京市神經(jīng)再生修復重點實驗室主任
重要學術(shù)論文
1.ZhouY,ZhangY,LiJ,LvF,ZhaoY,DuanD,XuQ*.Acomprehensivestudyonlong-terminjurytonigraldopaminergicneuronsfollowingintracerebroventricularinjectionoflipopolysaccharideinrats.JNeurochem.2012,123(5):771-80.SCI
2.ZengX,ShenH,ZhaoJ,CaiQ,WangC,XuQ*.Long-termchangesinmorphology,D2Rexpressionandtargetsofregenerateddopaminergicterminalsinthestriatumafterapartiallesioninthesubstantianigraintherat.BrainRes.2012,1450:166-73.SCI
3.XuC,ZhaoJ,LiuY,ZengX,JiaY,WangY,JiangX,XuQ*.Dopaminergicaxonspreferentiallyinnervatedendriticspineswithhyperactiveglutamatergicsynapsesintheratstriatum.BrainRes.2012,1486:92-102.SCI
4.WangY,WeiYT,ZuZH,JuRK,GuoMY,WangXM,XuQY*,CuiFZ.CombinationofHyaluronicAcidHydrogelScaffoldandPLGA.FarmaceuticalResearch.2011,28:1406-1414.SCI
5.Yue-TengWei,1Fu-ZhaiCui,1Qun-YuanXu*.Hyaluronicacidhydrogelmodifiedwithnogo-66receptorantibodyand.JOURNALOFBIOMEDICALMATERIALSRESEARCHB:APPLIEDBIOMATERIALS.2010,VOL95B,ISSUE1:110-117.SCI
6.JunpengZhao,YajuanYao,ChangleiXu,XiaohuaJiang,QunyuanXu*.Expressionoftheneuralspecificprotein,GAP-43,dramaticallylengthensthecellcycleinfibroblasts..Int.J.DevlNeuroscience.2009,27:531-537.SCI
7.LiangLi*,YujinSu*,ChunliZhao*QunyuanXu*.RoleofNurr1andRetininducingratembryonicneuralprecursorstodopaminergicneurons..NeurologicalResearch.2009,31:534-540.SCI
8.LinjiePan,YongjuanRen,FuzhaiCui,QunyuanXu*.ViabilityandDifferentiationofNeuralPrecursorsonHyaluronicAcidHydrogelScaffold.JournalofNeuroscienceResearch.2009,87:3207-3220.SCI
9.Yong-JuanRena,Zi-YouZhoua,Bing-FangLiub,Qun-YuanXub,Fu-ZhaiCuia.Preparationandcharacterizationoffibroin/hyaluronicacidcompositescaffold.InternationalJournalofBiologicalMacromolecules.2009,44:372–378.SCI
10.BLiu,JMa,EGao,YHe,FCui,QXu*.Developmentofanartificialneuronalnetworkwithpost-mitoticratfetalhippocampalcellsbyPolyethylenimine,BiosensorsandBioelectronics.BiosensorsandBioelectronics.2008,23:1221-1228.SCI
11.BWang,XZou,HZhang,DDuan,LJu,XJiang,XSun,CZhao,HZhao,JGuo,CXu,EGao,QXu*.EstablishmentofanimmortalizedGABAergicneuronalprogenitorcelllinefromembryonicventralmesencephalonintherat.BrainRes.2008,1210:63-75.SCI
12.Bing.fangLiu,Er.jingGao,Xian.zhiZeng,ManJi,QingCai,QiangLu,HuiYang,Qun.yuanXu*.Proliferationofneuralprecursorsinthesubventricularzoneafterchemicallesionsofthenigrostriatalpathwayinratbrain.BrainRes.2006,1106:30–39.SCI
13.S.HOU,W.TIAN,Q.XU,*F.CUI,J.ZHANG,Q.LUANDC.ZHAO.Theenhancementofcelladherenceandinducementofneuriteoutgrouthofdorsalrootgangliaco-culturedwithhyaluronicacidhydrogelsmodifiedwithNogo-66receptorantagonistinvitro.Neuroscience.2006,137:519-529.SCI
14.D.Chengyun,L.Guoming,M.Elia,M.V.Catania,X.Qunyuan*.Expressionofmultidrugresistancetype1gene(MDR1)P-glycoproteininintractableepilepsywithdifferentaetiologies:adouble-labellingandelectronmicroscopystudy.NeurolSci.2006,27:245–25.SCI
15.S.YU,J.Z.ZHANGANDQ.XU*.Genesassociatedwithneuronaldifferentiationofprecursorsfromhumanbrain.Neuroscience.2006,141:817–825.SCI
16.L.LI,,Y.SU,C.ZHAO,H.ZHAO,G.LIU,J.WANGANDQ.XU*.TheroleofRetreceptortyrosinekinaseindopaminergicneurondevelopment.Neuroscience.2006,142:391–400.SCI
17.B.F.Liu,J.Ma,Q.Y.Xu*,F.Z.Cui.Regulationofchargedgroupsandlamininpatternsforselectiveneuronaladhesion.ColloidsandSurfacesB:Biointerfaces.2006,53:175–178.SCI
18.J.Maa,B.F.Liub,Q.Y.Xub,F.Z.Cuia,.AFMstudyofhippocampalcellsculturedonsilicon.ColloidsandSurfacesB:Biointerfaces.2005,44:152-157.SCI
19.8.C.Niu,J.Li*,X.Cui,S.Han,P.Zu,H.Li,Q.Xu*.ChangesincPKCisoform-specificmembranetranslocationandproteinexpressioninthebrainofhypoxicpreconditionedmice.NeurosciLett.2005,384:1-6.SCI
20.W.M.Tiana,C.L.Zhanga,S.P.Houb,X.Yua,F.Z.Cuia,*,Q.Y.Xub,S.L.Shengc,.HyaluronicacidhydrogelasNogo-66receptorantibodydelivery.JournalofControlledRelease.2005,102:13-22.SCI
21.ShaopingHou,QunyuanXu,*,WeimingTian,FuzhaiCui,QingCai,JunMa,In-SoupLee.Therepairofbrainlesionbyimplantationofhyaluronicacidhydrogelsmodifiedwithlaminin..JNeurosciMethods.2005,148::60–70.SCI
22.ZouXF,XuQY*.Migrationanddifferentiationofbonemarrow-derivedstemcellsinthebrain.neurosciencebulletin.2005,21:425-431.無
23.ZHANGJINGZHONG,YANGHUI,DUANDEYI,DUANCHUNLI,ZHAOCHUNLI,SUNXIAOHONG,ZHANGJINLU,XUQUNYUAN*.Long-termtherapeuticeffectsonParkinsonianratsofintrastriatalco-graftswithgeneticallyengineeredfibroblastsexpressingtyrosinehydroxylaseandglialcellline-derivedneurotrophicfactor.Intern.Intern.J.Neuroscience.2005,115:689–699.SCI
24.DeyiDuan,HuiYang,JingzhongZhang,JinluZhang,QunyuanXu*.Long-termrestorationofnigrostriatalsystemfunctionbyimplantingGDNFgeneticallymodifiedfibroblastsinaratmodelofParkinson’sdisease..ExpBrainRes.2005,161:316-324.SCI
25.QunyuanXu,GunnarGrant*.Courseofspinocerebellaraxonsintheventralandlateralfuniculiofthespinalcordwithprojectionstotheposteriorcerebellarterminationarea:anexperimentalanatomicalstudyinthecat,usingaretrogradetracingtechnique.ExpBrainRes.2005,162:250–256.SCI
26.HaiyanZhang,YongmeiZha,ChunliZhao,ShuangYu,DeyiDuan,QunyuanXu*.Long-termexpansionofhumanneuralprogenitorcellsbyepigeneticstimulationinvitro.NeuroscienceResearch.2005,51:157-165.SCI
27.J.Ma,B.F.Liu,Q.Y.Xu,F.Z.Cui.AFMstudyofhippocampalcellsculturedonsiliconwaferswithnano-scalesurfacetopograph.ColloidsandSurfacesB:Biointerfaces.2005,44:152-157.SCI
28.S.Yu,J.Z.Zhang,C.L.Zhao,H.Y.Zhang&Q.Xu*.IsolationandcharacterizationoftheCD133+precursorsfromtheventricularzoneofhumanfetalbrainbymagneticaffinitycellsorting.BiotechnologyLetters.2004,26:1131-1136.SCI
主編或副主編的著作/譯著
1.
2.《格氏解剖學》,主譯,北京大學醫(yī)學出版社,200801
3.《解讀生命叢書》,主編,北京教育出版社,2002
4.《神經(jīng)生物學》,副主編,科學出版社,2002
5.《醫(yī)學神經(jīng)生物學》,副主編,高等教育出版社,2000
6.《腦內(nèi)細胞移植》,主編,福建科學技術(shù)出版社,2000
7.《世界最新英漢醫(yī)學詞匯(上下卷)》,主編,世界圖書出版公司,1999
重要獎項
1.用組織工程技術(shù)修復中樞神經(jīng)系統(tǒng)損傷的實驗研究中華醫(yī)學科技獎三等201112
2.用改性透明質(zhì)酸水凝膠修復中樞神經(jīng)系統(tǒng)損傷的實驗研究北京市科學技術(shù)獎三等201111
3.高等學校教學名師獎教育部200909
4.中華醫(yī)學科技獎三等200612
5.后肢運動的中樞下行控制的研究北京科技進步三等獎(第二)2004
6.醫(yī)學神經(jīng)生物學全國高等院校優(yōu)秀教材一等獎(第二)2002
7.高校領(lǐng)導干部理論學習北京市教工委二等(第一)2002
8.GDNF和TH轉(zhuǎn)基因細胞腦內(nèi)聯(lián)合移植治療帕金森氏病大鼠模型的研究北京市科技進步二等獎(第一)2001
9.腦內(nèi)細胞移植華東地區(qū)出版社優(yōu)秀圖書二等獎(第一)2001
10.中樞神經(jīng)系統(tǒng)解剖學CAI課件的開發(fā)、應用北京市教育教學成果一等獎(第一)2001
11.人腦血管和臨床北京市科技進步二等獎(第三)1998
12.基因治療巴金森病大鼠模型的實驗研究衛(wèi)生部科技進步三等獎(第一)1997
13.基因治療巴金森病大鼠模型的實驗研究北京市科技進步二等獎(第一)1997
14.關(guān)于脊髓小腦束結(jié)構(gòu)的研究衛(wèi)生部科技進步二等獎(第一)1994
15.關(guān)于脊髓小腦束結(jié)構(gòu)的研究北京市科技進步二等獎(第一)1994
16.HRP-ACHE雙重組化法研究大鼠脊髓小腦束ACHE陽性神經(jīng)元北京市科技進步學術(shù)獎(第二)1987
17.應用放射自顯影法對大鼠伏膈核離心纖維系統(tǒng)的觀察,應用辣根過氧化物酶法研究伏膈核傳入纖維的聯(lián)系衛(wèi)生部乙級科技成果獎(第一)1981
18.伏膈核傳入傳出纖維的聯(lián)系北京市科技進步學術(shù)獎(第一)1980
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