浙江大學醫(yī)學院導師：湯慧芳 正文

　　姓名：湯慧芳
　　性別：女
　　所在學院：醫(yī)學院
　　職稱：副教授

　　研究方向：
　　呼吸藥理學,包括哮喘、急性肺損傷、COPD等肺部炎癥的發(fā)病機制及藥物治療。

　　個人簡介
　　2005年浙江大學醫(yī)學院藥理教研室藥理學博士畢業(yè)并獲博士學位，2007年晉升副教授，從事藥理學科研和教學工作至今。主要從事呼吸藥理學、抗炎免疫藥理學和臨床藥理學研究。
　　Publications
　　1．Xie QM, Tang HF, Chen JQ, Bian RL. Pharmacological actions of tetrandrine in inflammatory pulmonary diseases. Acta Pharmacol Sin. 2002 Dec;23(12):1107-13. Review.
　　2．Tang HF, Song YH, Chen JC, Chen JQ, Wang P. Upregulation of phosphodiesterase-4 in the lung of allergic rats. Am J Respir Crit Care Med. 2005 Apr 15;171(8):823-8.
　　3．Tang HF, Chen JQ, Xie QM, Adcock Ian. The role of PDE4 in pulmonary inflammation and goblet cell hyperplasia in allergic rats. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2006, May;1762(5):525-32.
　　4．Tang HF, Chen JQ, Xie QM. Upregulation of PDE4 activity and expression in lung of asthmatic rats. Acta Pharmacol Sin. 2006.7(suppl 1): 384
　　5．Li ZG, Zhou L, Tang HF. Effects of levobupivacaine and bupivacaine on rat myometrium. J Zhejiang Univ Sci B. 2006 Sep;7(9):757-62.
　　6．Deng YM, Xie QM, Tang HF, Sun JG, Deng JF, Chen JQ, Yang SY. Effects of ciclamilast, a new PDE 4 PDE4 inhibitor, on airway hyperresponsiveness, PDE4D expression and airway inflammation in a murine model of asthma. Eur J Pharmacol. 2006 Oct 10;547(1-3):125-35.
　　7．Sun JG, Deng YM, Wu X, Tang HF, Deng JF, Chen JQ, Yang SY, Xie QM. Inhibition of phosphodiesterase activity, airway inflammation and hyperresponsiveness by PDE4 inhibitor and glucocorticoid in a murine model of allergic asthma. Life Sci. 2006 Oct 26;79(22):2077-85.
　　8．Tang HF, Chen JQ, Wang P. The potential role of phosphodiesterases in the development of multiple organ dysfunction syndrome. Journal of Organ Dysfunction. 2007, 3　(1):18-30
　　9．Zheng YY, Lan YP, Tang HF, Zhu SM. Propofol pretreatment attenuates aquaporin-4 over-expression and alleviates cerebral edema after transient focal brain ischemia reperfusion in rats. Anesth Analg. 2008 Dec;107(6):2009-16.
　　10．Wang YJ, Jiang YL, Tang HF, Zhao CZ, Chen JQ. Zl-n-91, a selective phosphodiesterase 4 inhibitor, suppresses inflammatory response in a COPD-like rat model. Int Immunopharmacol. Feb;10(2):252-8
　　11．Tang HF, Lu JJ, Tang JF, Zheng X, Liang YQ, Wang XF, Wang YJ, Mao LG, Chen JQ. Action of a Novel PDE4 inhibitor ZL-n-91 on lipopolysaccharide -induced acute lung injury. Int Immunopharmacol. 2010 Apr;10(4):406-11

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